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. 2021 Jul 12;134(16):1897–1907. doi: 10.1097/CM9.0000000000001628

Figure 2.

Figure 2

ROS-related treatments of patients with leukemia. Oxidative stress treatment of leukemia includes vitamin antioxidants, natural plant-derived antioxidants, endogenous antioxidants (including enzymatic and non-enzymatic antioxidants), targeted oxidative stress therapy, induced autophagy therapy, etc. Antioxidant therapy in combination with chemotherapy or other strategies may be a promising treatment for leukemia. AMPK: 5′ adenosine-monophosphate (AMP)-activated protein kinase; ATO: Arsenic trioxide; BAP: Biological antioxidant potential; D-ROM: Derived active oxygen metabolites; GPx3: Glutathione peroxidase 3; HO-1: Heme oxygenase-1; MDA: Malondialdehyde; PC: Phosphatidylcholine; ROS: Reactive oxygen species.