Table 3.
RBD-IgG and neutralizing antibodies following second vaccine dose
| Study group | Positive RBD-IgG, n/N (%) | RBD-IgG GMT (95% CI) | Positive NA/positive RBD-IgG, n/N (%) | NAa GMT (95% CI) |
|---|---|---|---|---|
| Controlsb | 258/261 (98.9) | 6.1 (5.8–6.4) | 197/201 (98) | 482.8 (410.8–567.5) |
| HIV-1 | 139/143 (97.2) | 5.2 (4.8–5.5) | 131/135 (97) | 449.0 (366.6–550.0) |
Abbreviations: GMT, geometric mean titre; HIV-1, human immunodeficiency virus type 1; NA, neutralizing antibodies; RBD, receptor-binding domain; Vx, vaccination.
a
Only samples with neutralizing antibody titres above the cut-off (>8) were included in the analysis for GMT-NA.
b
Controls, health-care workers without immunosuppression.