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. 2021 Aug 24;56(10):869–880. doi: 10.1007/s00535-021-01817-9

Table 2.

Criteria for study quality

Representative cohort Items Consecutively enrolled Not consecutive/prospective Not consecutive, retro, case / NA
Risk of bias Very low Low High
Point 2 1 0
Ascertainment of exposure Items International criteria National diagnostic criteria Non-validated criteria/NA
Risk of bias Very low Low High
Point 2 1 0
Demonstration that outcome of interest was not present Items Yes No NA
Risk of bias Very low Low High
Point 2 1 0
Initial steroid dose (daily) Items 0.6 mg/kg or 3–40 mg 1 mg/kg or more NA
Risk of bias Very low Low High
Point 2 1 0
Dose of AZA (daily) Items 2–2.5 mg/kg or 50–100 mg Less than 2 mg/kg or 50 mg NA
Risk of bias Very low Low High
Point 2 1 0
Record of how to use immunosupressor drugs Items Yes No NA
Risk of bias Very low Low High
Point 2 1 0
Assessment of effectiveness of treatments for relapse AIP Items Yes No/NA
Risk of bias Very low High
Point 2 0
Relapse definition Items Clinical and radiologic relapse Clinical or radiologic relapse Not a clear
Risk of bias Very low Low High
Point 2 1 0
Sufficient follow-up evaluation Items  > 2 y  ≤ 2 y Undefined
Risk of bias Very low Low High
Point 2 1 0
Adequacy of F/U schedule Items Definite schedule Undefinite
Risk of bias Very low High
Point 2 0