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. 2021 Aug 23;11:17019. doi: 10.1038/s41598-021-95955-y

Table 4.

Odds Ratios (ORs) and 95% Confidence Intervals (CIs) for breast cancer associated with the Dietary Inflammatory Index (DII).

Case/control Quartiles of DII p-trend P-interaction
Q1 Q2 Q3 Q4
OR 95% CI OR 95% CI OR 95% CI OR 95% CI
Department
Côte d'Or 239/ 307 1.00 Reference 1.56 0.89, 2.72 1.82 1.06, 3.12 1.33 0.77, 2.31 0.24
Ille-et-Vilaine 633/ 659 1.00 Reference 0.89 0.64, 1.24 1.24 0.90, 1.71 1.29 0.93, 1.80 0.05 0.95
BMI (pre-menopausal)
 ≤ 25 kg/m2 275/257 1.00 Reference 1.19 0.68, 2.10 1.43 0.83, 2.47 1.36 0.81, 2.29 0.21
 > 25 kg/m2 71/118 1.00 Reference 0.60 0.22, 1.69 0.68 0.26, 1.75 0.98 0.40, 2.36 0.97 0.61
BMI (post-menopausal)
 ≤ 25 kg/m2 286/321 1.00 Reference 0.72 0.44, 1.18 1.10 0.69, 1.76 1.10 0.67, 1.79 0.46
 > 25 kg/m2 240/270 1.00 Reference 1.61 0.96, 2.70 2.23 1.32, 3.77 1.62 0.92, 2.83 0.02 0.35
Physical activity
Inactive 255/ 256 1.00 Reference 1.26 0.69, 2.30 2.17 1.25, 3.79 1.43 0.83, 2.46 0.09
Active 617/ 710 1.00 Reference 0.97 0.70, 1.34 1.13 0.82, 1.55 1.28 0.92, 1.77 0.12 0.49
Tobacco smoking
Never smokers 524/ 589 1.00 Reference 0.91 0.63, 1.32 1.28 0.90, 1.81 1.04 0.72, 1.50 0.45
Ever smokers 348/ 377 1.00 Reference 1.27 0.81, 1.97 1.44 0.91, 2.26 1.71 1.11, 2.65 0.01 0.43
Alcohol drinking
 ≤ 1 glass/week 345/ 351 1.00 Reference 0.88 0.55, 1.42 1.52 0.97, 2.38 1.38 0.89, 2.13 0.05
 > 1 glass/week 527/ 615 1.00 Reference 1.17 0.82, 1.67 1.36 0.96, 1.92 1.23 0.86, 1.76 0.16 0.93

Stratification by selected breast cancer risk factors. The CECILE study, France, 2005–2007.

P trend determined from the model using the median value in each quartile as a quantitative variable.

Odds ratios adjusted for study area, age at reference date, history of benign breast, family history of breast cancer in first-degree relatives, age at menarche, parity, age at first full-term pregnancy, breast feeding, menopausal status, current use of hormone therapy, oral contraceptive use and body mass index.

No adjustment on the stratification variable.