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. 2021 Aug 17;62(9):792–798. doi: 10.3349/ymj.2021.62.9.792

Table 3. Hazard Ratios Per 1 SD Increment (95% CI) of Cancer Incidence of UA, Albumin, and Total Bilirubin within the Normal Range.

UA Albumin Total bilirubin
Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Cancer incidence (n=1348) 1.04 (0.98–1.10) 1.02 (0.96–1.08) 0.93 (0.89–0.98) 0.93 (0.88–0.98) 0.94 (0.89–1.00) 0.95 (0.90–1.00)
Stomach (n=250) 0.95 (0.83–1.09) 0.93 (0.81–1.07) 0.99 (0.88–1.12) 0.97 (0.86–1.10) 0.91 (0.80–1.03) 0.92 (0.81–1.05)
CRC (n=197) 1.14 (0.98–1.34) 1.13 (0.96–1.32) 1.03 (0.90–1.19) 1.00 (0.87–1.15) 0.88 (0.76–1.01) 0.89 (0.77–1.03)
Lung (n=198) 0.91 (0.78–1.06) 0.94 (0.81–1.10) 0.83 (0.72–0.96) 0.82 (0.72–0.94) 0.85 (0.74–0.98) 0.89 (0.77–1.03)
Thyroid (n=123) 1.07 (0.86–1.33) 1.01 (0.80–1.26) 1.01 (0.84–1.21) 1.07 (0.89–1.28) 1.06 (0.88–1.27) 1.05 (0.87–1.27)
Prostate (n=83) 1.26 (0.99–1.59) 1.23 (0.97–1.57) 1.06 (0.86–1.30) 1.07 (0.86–1.32) 1.09 (0.89–1.34) 1.08 (0.87–1.33)
Liver (n=69) 1.03 (0.79–1.33) 0.99 (0.76–1.29) 0.54 (0.43–0.68) 0.53 (0.42–0.66) 1.16 (0.92–1.46) 1.19 (0.94–1.50)
Breast (n=49) 1.06 (0.75–1.50) 0.96 (0.67–1.38) 1.07 (0.81–1.43) 1.06 (0.79–1.43) 1.34 (1.02–1.77) 1.27 (0.95–1.70)
Others (n=379) 1.09 (0.97–1.22) 1.07 (0.95–1.20) 1.00 (0.91–1.11) 0.99 (0.89–1.10) 0.89 (0.81–0.99) 0.89 (0.80–0.99)
Cancer death (n=509) 0.99 (0.90–1.08) 1.01 (0.91–1.11) 0.89 (0.82–0.97) 0.88 (0.80–0.95) 0.87 (0.79–0.95) 0.89 (0.82–0.98)

SD, standard deviation; CI, confidence interval; UA, uric acid; N, number of cancer incidence or deaths; CRC, colorectal cancer.

Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex, smoking, alcohol drinking, physical activity, education levels, body mass index, family history of diabetes, and serum high density lipoprotein cholesterol levels.