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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Infect Control Hosp Epidemiol. 2021 Feb 24;42(12):1437–1444. doi: 10.1017/ice.2021.21

Table 1.

Guideline-recommended antibiotic therapy for acute uncomplicated cystitis by antibiotic agent and duration, adapted from the 2011 IDSA clinical practice guidelines for the treatment of acute uncomplicated cystitis in women.8

Antibiotic agent Recommended duration
First-line regimen
 Nitrofurantoin 5 days
 Trimethoprim-sulfamethoxazole 3 days
 Fosfomycin trometamol 1 day
Non-first-line regimen
 Fluoroquinolones 3 days
 β-Lactams 3–7 days
 Trimethoprim monotherapy 3 days