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. 2021 Aug 23;4:997. doi: 10.1038/s42003-021-02524-0

Fig. 8. Indole and intestinal microbial products from indole and probiotic treated mice increase AhR activation.

Fig. 8

a Dose–response curves of indole in the DR-EcoScreen assay. DR-EcoScreen cells were treated with increasing concentrations of indole, to detect AhR agonistic activity. b Dose–response curves of intestinal microbial products in the DR-EcoScreen assay. c Intestinal microbial products were isolated from binge-on-chronic alcohol-fed mice with and without treatment AhR agonistic activity was determined using the DR-EcoScreen assay. Bars represent the mean ± SEM and dots represent individual mice. P values are indicated in the figure and were determined by one‐way ANOVA with Sidak’s multiple comparison test. N = 5–6/group.