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. 2021 Aug 10;9:711400. doi: 10.3389/fped.2021.711400

Table 2.

mean plasma concentration of GH, IGF1 and insulin at day 3, 10 and 30 [mean ± standard deviation (min-max)].

GH (mIU/L) IGF1 (ng/ml) Insulin (mIU/L)
Day 3 All ( n = 51) 50 ± 41 (5–208) 9 ± 8 (1–29) 27 ± 46 (1–307)
<28 weeks GA 42 ± 37 (11–110) 5.8 ± 6 (1–23) 34 ± 35 (2–131)
AGA (n = 32) 38 ± 28 (6–110) 8 ± 8 (2–29) 25 ± 26 (1–131)
SGA (n = 19) 70 ± 51 (5–208)** 10 ± 7 (1–25) 31 ± 74 (1–307)
Insulin (n = 14) 44 ± 38 (5–110) 5 ± 7 (1–23) 56 ± 83 (5–208)
No insulin (n = 47) 52 ± 42 (6–208) 10 ± 8 (1–29) 18 ± 20 (1–80)
Day 10 All ( n = 34) 38 ± 25 (5–148) 21 ± 12 (1–40) 16 ± 16 (1–80)
<28 weeks GA 43 ± 44 (5–148) 11 ± 8 (1–25) 31 ± 25 (7–80)
AGA (n = 26) 38 ± 28 (5–148) 19 ± 12 (1–40) 18 ± 19 (1–80)
SGA (n = 8) 38 ± 10 (23–52) 29 ± 10 (13–39)* 11 ± 8 (1–23)
Insulin (n = 10) 39 ± 42 (5–148) 16 ± 8 (1–25) 30 ± 23 (12–80)*
No insulin (n = 24) 38 ± 16 (12–75) 24 ± 13 (1–40) 10 ± 9 (1–36)
Day 30 All ( n = 25) 47 ± 29 (14–144) 26 ± 13 (1–48) 14 ± 14 (1–61)
<28 weeks GA 48 ± 26 (21–80) 18 ± 12 (1–48) 12 ± 6 (1–21)
AGA (n = 23) 43 ± 20 (14–82) 25 ± 13 (1–48) 15 ± 14 (1–61)
SGA (n = 2) (35–144) (37–40) (2)
Insulin (n = 8) 42 ± 27 (14–80) 23 ± 15 (13–48) 13 ± 5 (7–21)
No insulin (n = 17) 50 ± 32 (17–144) 29 ± 11 (13–45) 15 ± 16 (1–61)
*

p < 0.05

**

p < 0.01 for comparison between AGA vs. SGA or insulin vs. no insulin groups.