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. 2021 Aug 10;8:698495. doi: 10.3389/fmed.2021.698495

Table 2.

Sensitivity and specificity of NDO-HSA, LID-1 and NDO-LID antigens in IgA-based serodiagnosis of MB and PB leprosy.

Antigens Clinical form Cutoffa Sensitivityb (%) Specificityb(%) Area under the curve
NDO-HSA MB 0.31 100 95 0.994
PB 0.244 95 85 0.937
LID-1 MB 0.65 78 95 0.917
PB 0.412 95 50 0.746
NDO-LID MB 0.64 89 100 0.978
PB 0.158 99 30 0.642
a

, cutoff, sensitivity and specificity data were determined based on the analysis of receiver operating characteristic (ROC) curves;

b

, the values of sensitivity and specificity were determined according to the point of the ROC curve nearest to the point of sensitivity and specificity equal to 100%.