Table 2.
Sensitivity and specificity of NDO-HSA, LID-1 and NDO-LID antigens in IgA-based serodiagnosis of MB and PB leprosy.
| Antigens | Clinical form | Cutoffa | Sensitivityb (%) | Specificityb(%) | Area under the curve |
|---|---|---|---|---|---|
| NDO-HSA | MB | 0.31 | 100 | 95 | 0.994 |
| PB | 0.244 | 95 | 85 | 0.937 | |
| LID-1 | MB | 0.65 | 78 | 95 | 0.917 |
| PB | 0.412 | 95 | 50 | 0.746 | |
| NDO-LID | MB | 0.64 | 89 | 100 | 0.978 |
| PB | 0.158 | 99 | 30 | 0.642 |
a
, cutoff, sensitivity and specificity data were determined based on the analysis of receiver operating characteristic (ROC) curves;
b
, the values of sensitivity and specificity were determined according to the point of the ROC curve nearest to the point of sensitivity and specificity equal to 100%.