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. 2021 Aug 10;12:673443. doi: 10.3389/fpsyt.2021.673443

Table 3.

Results of ANCOVA.

HCs ( n = 400) MDD ( n = 37) Age-by-group interaction Effect of group
Median SD Median SD df F-value p-value F-value p-value
Free-viewing test
Number of fixations 23.00 3.32 21.50 4.93 1,433 5.07 2.5 × 10−2* N/A N/A
Duration of fixation 254.50 46.30 267.00 86.41 1,433 5.51 1.9 × 10−2* N/A N/A
Number of saccades 21.00 3.80 20.00 5.33 1,433 7.19 7.6 × 10−3* N/A N/A
Duration of saccades 42.38 5.59 42.50 6.65 1,433 0.10 0.75 0.91 0.34
Saccade amplitude 4.00 1.17 3.60 0.99 1,433 0.00 0.99 0.66 0.42
Average saccade velocity 93.94 19.25 81.99 17.50 1,433 0.12 0.73 2.51 0.11
Peak saccade velocity 185.10 44.55 181.81 43.85 1,433 0.73 0.39 0.01 0.91
Scanpath length 110.70 28.81 92.56 34.98 1,433 2.19 0.14 8.30 4.2 × 10−3**
Fixation density 0.88 0.39 0.92 0.51 1,433 9.58 2.1 × 10−3* N/A N/A
Main sequence vmax 436.81 119.83 419.68 107.90 1,433 0.39 0.53 0.41 0.52
Main sequence s 9.29 4.40 7.63 3.95 1,433 0.00 0.95 0.13 0.72
Main sequence v0 33.93 9.88 32.60 10.27 1,433 0.57 0.45 0.01 0.94
Number of blinks 1.00 1.49 1.00 1.31 1,433 3.64 0.06 0.45 0.50
Smooth pursuit test
Horizontal SNR 2.03 0.16 2.02 0.18 1,433 2.74 0.10 0.00 0.95
Horizontal position gain 1.01 0.03 1.00 0.03 1,433 0.93 0.33 0.34 0.56
Horizontal RMSE 8.35 4.18 8.78 4.11 1,433 2.30 0.13 0.39 0.53
Vertical SNR 1.84 0.20 1.80 0.20 1,433 1.22 0.27 0.27 0.60
Vertical position gain 0.96 0.07 0.95 0.09 1,433 0.67 0.41 1.18 0.28
Vertical RMSE 14.03 7.94 13.83 9.69 1,433 1.56 0.21 0.15 0.70
Number of fixations 58.25 13.77 60.00 13.99 1,433 0.17 0.68 1.00 0.32
Duration of fixations 259.88 69.00 250.75 79.92 1,433 1.29 0.26 4.27 0.04
Number of saccades 56.00 15.71 59.50 13.85 1,433 0.16 0.69 0.73 0.39
Duration of saccades 30.13 5.63 34.50 9.41 1,433 3.62 0.06 8.54 3.7 × 10−3**
Saccade amplitude 1.94 0.62 2.38 0.71 1,433 3.22 0.07 5.40 0.02
Average saccade velocity 65.13 11.71 70.80 9.85 1,433 0.00 0.96 1.42 0.23
Peak saccade velocity 98.05 38.71 136.46 46.52 1,433 2.32 0.13 8.41 3.9 × 10−3**
Horizontal velocity gain 0.85 0.11 0.77 0.14 1,433 0.85 0.36 4.60 0.03
Vertical velocity gain 0.76 0.13 0.70 0.16 1,433 0.59 0.44 1.43 0.23
Number of blinks 1.00 4.00 1.00 2.57 1,433 0.10 0.76 0.24 0.62
Fixation stability test
Number of fixations 3.00 2.46 3.25 2.71 1,433 0.25 0.62 0.10 0.75
Duration of fixation 2057.19 1492.87 1422.50 1558.35 1,433 0.21 0.64 0.50 0.48
Number of saccades 1.50 2.30 2.00 2.53 1,433 0.91 0.34 0.04 0.85
Scanpath length 1.13 2.21 1.36 2.43 1,433 0.23 0.63 0.02 0.89
Number of microsaccades 6.25 3.51 6.50 4.17 1,433 0.46 0.50 0.13 0.72
Number of blinks 0.00 0.97 0.00 0.70 1,433 2.68 0.10 0.04 0.84

RMSE, Root mean square error; SNR, signal-to-noise ratio; N/A, not applicable.

*

p < 0.05.

**

Represents significant after false discovery rate correction.