Figure 2.

miR-125a-5p and miR-7 inhibited the PDGF-BB-stimulated proliferation of VSMCs. PDGF-BB-treated VSMCs were transfected with miR-125a-5p mimics or inhibitors, miR-7 mimics or inhibitors or negative controls. Cell growth was detected by Cell Counting kit-8 (A) and (B) EdU assays (magnification, ×100). (C) The expressions of proliferative genes were examined using western blotting. ^##P<0.01 vs. NC mimics; **P<0.01 vs. NC inhibitors. miR, microRNA; PDGF-BB, platelet-derived growth factor BB; VSMCs, vascular smooth muscle cells; NC, negative control; OD, optical density; p-p38, anti-phosphorylated-p38.