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. 2021 Aug 10;12:708959. doi: 10.3389/fimmu.2021.708959

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Copyright © 2021 Fontes-Cal, Mattos, Medeiros, Pinto, Belchior-Bezerra, Roque-Souza, Dutra, Ferrari, Vidigal, Faria, Couto and Gomes

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plasma levels of cytokines. (A) Plasma levels (pg/mL) of IL-12, TNF, IL-6, IL1β, and IL-10 cytokines assayed by flow cytometry. (B) Ratio between IL-10 and IL-6 in healthy individuals and patients with NAFL and NASH. The groups evaluated were healthy individuals (Control, n=11) and patients with simple steatosis (NAFL, n=16) and nonalcoholic steatohepatitis (NASH, n=15). Significant differences (p < 0.05) between groups are evidenced by lines and asterisks (*) according to unpaired Kruskal-Wallis test (nonparametric data), followed by Dunn’s post hoc test. *p < 0.05.