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. 2021 Aug 10;12:708959. doi: 10.3389/fimmu.2021.708959

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Copyright © 2021 Fontes-Cal, Mattos, Medeiros, Pinto, Belchior-Bezerra, Roque-Souza, Dutra, Ferrari, Vidigal, Faria, Couto and Gomes

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokines correlations networks. The groups evaluated were healthy individuals (Control, n=11) and patients with simple steatosis (NAFL, n=16) and nonalcoholic steatohepatitis (NASH, n=15). Correlation networks between cytokines of control (A), NAFL (B), and NASH (C) groups. Strong correlations present σ higher than 0.63 and are represented by thick lines. Moderate correlations present σ between 0,62-0,40 and are represented by thin lines. The continuous lines represent positive correlations and the traced lines represent the negative correlations. Statistical significance was defined by p < 0.05.