Table 1. Patient Baseline Characteristics.
| Characteristic | No. (%) | ||
|---|---|---|---|
| Standard group (n = 55) | High-dose group (n = 52) | Total (n = 107) | |
| Age, mean (SD), y | 48.2 (12.9) | 45.6 (13.7) | 47.0 (13.3) |
| Sex | |||
| Men | 41 (74.5) | 40 (76.9) | 81 (75.7) |
| Women | 14 (25.5) | 12 (23.1) | 26 (24.3) |
| BMI, mean (SD) | 27.0 (5.1) | 27.5 (4.2) | 27.3 (4.7) |
| Alcohol consumption | 31 (57.4) | 27 (52.9) | 58 (55.2) |
| Substance abuse | 5 (9.3) | 6 (11.5) | 11 (10.4) |
| Active smoker | 22 (40.7) | 22 (43.1) | 44 (41.9) |
| Diabetes | 3 (5.6) | 2 (4.0) | 5 (4.8) |
| Arterial hypertension | 16 (29.1) | 12 (23.5) | 28 (26.4) |
| Dyslipidemia | 37 (69.8) | 23 (46.9) | 60 (58.8) |
| Syphilis | 4 (7.3) | 8 (16.0) | 12 (11.4) |
| Hepatitis C virus infection | 0 | 1 (2.0) | 1 (0.9) |
| CD4 count, mean (SD), cells/mm3 | 424 (210) | 412 (201) | 418 (205) |
| Nadir CD4 count, (SD), cells/mm3 | 150.5 (17) | 123.5 (17) | 136.4 (115) |
| CD8 count, mean (SD), cells/mm3 | 887 (450) | 1000 (497) | 941 (474) |
| CD4/CD8 ratio, mean (SD) | 0.58 (0.33) | 0.49 (0.32) | 0.54 (0.33) |
| Hepatitis C virus infection | 0 | 1 (2.0) | 1 (0.9) |
| Antiretroviral therapy | 54 (98.2) | 51 (98.0) | 105 (98.1) |
| Undetectable viral load | 49 (89.1) | 43 (83.0) | 92 (86.0) |
| Time living with HIV, median (IQR), mo | 92 (46-158) | 77 (46-122) | 85 (46-142) |
| Time using ART, median (IQR), mo | 58 (32-112) | 55 (32-94) | 56 (32-109) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range.