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In vivo effect of KMT5B overexpression. (A) Mock or KMT5B-transfected LN-229 cells were subcutaneously injected into the flanks or the neck base of 4 nude mice. An image of the tumors excised after animal sacrifice is shown on the left. Tumor growth was monitored for 56 days [General linear model (GLM) ***p-value < 0.001]. (B) Box plot represents average tumor weights for the tumors generated by each clone (Wilcoxon rank sum tests; *p < 0.05; **p < 0.01).
