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. Author manuscript; available in PMC: 2021 Aug 24.
Published in final edited form as: Nat Genet. 2020 Aug 17;52(9):908–918. doi: 10.1038/s41588-020-0642-1

Figure 7 |. Schematic diagram of the self-renewal of Dist-Luminal-C cells and their role as prostate cancer-initiating cells.

Figure 7 |

Dist-Luminal-C cells are located in invagination tips of the mouse prostate. Luminal-C cells undergo self-renewal in prostate invagination tips during mouse prostate regression and regeneration. Dist-Luminal-C cells can serve as the cellular origin of prostate cancer.