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. 2021 Aug 24;19:201. doi: 10.1186/s12916-021-02061-x

Table 2.

Spearman’s rank correlations between C1q fixation and antibodies to VAR2CSA DBL5 and DBL3 domains

Ig C1q fixation
DBL5 DBL3
Total IgG 0.76 0.75
IgG1 0.58 0.51
IgG2 0.46 0.35
IgG3 0.56 0.40

All correlations were statistically significant; P<0.001. IgG4 responses were not detectable in this cohort. N=302