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. 2021 Aug 23;22(1):99. doi: 10.1186/s10194-021-01310-x

Table 6.

Migraine costs (population estimates)

Luxembourg
N = 124,713
Russia
N = 18,122,512
Spain
N = 10,772,263
Cost (euros)
1-year estimate
Cost (euros)
5-year estimate
Cost (euros)
1-year estimate
Cost (euros)
5-year estimate
Cost (euros)
1-year estimate
Cost (euros)
5-year estimate
CURRENT CARE: NO CONSUMER EDUCATION OR HEALTH-CARE PROFESSIONAL TRAINING
 Primary analysis
  Medications
   acute non-specific ASA 1 g 7568 35,364 855,296 3,996,867 508,399 2,375,791
   acute-specific sumatriptan 50 mg 3635 16,986 1,207,420 5,642,371 251,626 1,175,870
   prophylaxis amitriptyline 100 mg/day 695 3249 195,304 912,670 20,816 97,276
   Total medications 11,898 55,599 2,258,020 10,551,908 780,841 3,648,937
  Health-care provision
   GP visits 1,868,796 6,153,787 133,597,931 493,496,811 185,508,849 725,403,433
   specialist visits 708,809 708,809 126,073,602 126,073,602 125,445,228 125,445,229
   MRI 361,613 361,613 77,008,823 77,008,823 73,240,116 73,240,116
   Total health-care provision 2,939,218 7,224,209 336,680,356 696,579,236 384,194,193 924,088,778
  Secondary analyses
   Total lost productivity 120,885,706 564,908,477 2,045,525,786 9,558,904,021 4,136,426,354 19,329,847,995
   Sensitivity analysis: disability accounts for 20% lost productivity 24,177,141 112,981,695 409,105,157 1,911,780,804 827,285,271 3,865,969,599
TARGET CARE: WITH CONSUMER EDUCATION AND HEALTH-CARE PROFESSIONAL TRAINING
 Primary analysis
  Medications
   acute non-specific ASA 1 g 16,564 77,405 1,498,933 7,004,632 370,931 1,733,392
   acute-specific sumatriptan 50 mg 153,854 718,974 50,269,478 234,913,251 10,313,113 48,193,995
   prophylaxis amitriptyline 100 mg/day 30,050 140,425 7,857,564 36,719,020 899,802 4,204,845
   Total medications 200,468 936,804 59,625,975 278,636,903 11,583,846 54,132,232
  Health-care provision
  GP visits 4,357,297 12,893,134 373,410,366 1,104,912,154 399,420,967 1,181,876,886
  specialist visits 611,042 611,042 74,160,942 74,160,942 46,119,569 46,119,569
   MRI 62,347 62,347 9,059,861 9,059,861 5,385,303 5,385,303
  Total health-care provision 5,030,686 13,566,523 456,631,169 1,188,132,957 450,925,839 1,233,381,758
 Secondary analyses
  Total lost productivity 5,431,622 373,419,228 1,296,237,360 6,057,419,858 2,621,228,447 12,249,208,158
  Sensitivity analysis: disability accounts for 20% lost productivity 1,086,324 74,683,846 259,247,472 1,211,483,972 524,245,689 2,449,841,632