FIGURE 4.

The extent of renal interstitial fibrosis (% area of tissue images affected by lesion) induced by chronic HS (4% NaCl in diet) intake + AngII (25 ng/min) treatment for 4 weeks was significantly attenuated in TNFR2KO (n = 5) but not in TNFR1KO (n = 6) compared to wild‐type (n = 7) mice. The extent of interstitial fibrosis by Gomori's trichrome staining images are illustrated in (a, b, and c) and the mean values of the percent area of these lesions are shown in graph (d). Arrows indicating the important trichrome stained images