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. 2021 Aug 10;12:656663. doi: 10.3389/fimmu.2021.656663

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Copyright © 2021 Wang, Yin, Ma, Ge, Lang, Sun, He, Fu, Sun, Yu, Zhang, Cui, Han, Xu, Ding, Chu, Shang, Wu and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IP-10 promotes HIV AD8 and NL4-3 infection of resting memory CD4⁺ T cells. (A) Gating strategy for isolating a pure population of resting memory CD4⁺ T cells. (B) Schematic illustration of the procedure for evaluating the role of IP-10 in HIV infection of resting memory CD4⁺ T cells. (C) Kinetics of the effect of AD8 (n = 6)/NL4-3(n = 11), AD8/NL4-3+IP-10, AD8/NL4-3+IP-10+mAb, and AD8/NL4-3+IP-10+CXCR3 on resting memory CD4⁺ T cell from 2 representative NCs. P24 levels were compared between groups on the 14^th day post infection by one-way analysis of variance. *P < 0.05.