Table V.
NLRP3 mRNA expression of PBMCs/neutrophils indifferent genotypes of rs4612666 and rs10754558 in patients with RA.
| A, PBMCs | |||
|---|---|---|---|
| Genotype | Number | M (P25,P75) | P-value |
| rs4612666 | 0.811 | ||
| CC | 12 | 0.980 (0.665,1.320) | |
| CT | 26 | 0.930 (0.790,1.115) | |
| TT | 11 | 0.855 (0.773,1.240) | |
| rs10754558 | 0.077 | ||
| GG | 9 | 1.180 (0.870,1.260) | |
| CG | 21 | 0.830 (0.720,1.130) | |
| CC | 19 | 0.930 (0.825,1.183) | |
| B, Neutrophils | |||
| Genotype | Number | M (P25,P75) | P-value |
| rs4612666 | 0.187 | ||
| CC | 12 | 1.260 (0.945,1.573) | |
| CT | 26 | 0.945 (0.795,1.280) | |
| TT | 11 | 0.950 (0.785,1.510) | |
| rs10754558 | 0.424 | ||
| GG | 9 | 1.070 (0.950,2.350) | |
| CG | 21 | 1.000 (0.820,1.335) | |
| CC | 19 | 0.850 (0.740,1.430) |
All the mRNA expression levels were showed as median value (interquartile range); NLRP3, NOD-, LRR- and pyrin domain-containing protein 3; PBMC, peripheral blood mononuclear cells; RA, rheumatoid arthritis; M, median value.