Figure 5.

KIF2C contributes to tumor growth of hepatocellular carcinoma cells in mice. (A) Hep3B cells infected with control or KIF2C shRNA lentivirus were subcutaneously implanted into nude mice. After 15 days, tumors were imaged and tumor volume was measured every 4 days. Tumor growth curves were compared between KIF2C-depleted and control groups. Scale bar, 5 mm. (B) Western blot assays were used to detect the expression levels of KIF2C in tumors from control or KIF2C-depletion groups. (C) Immunohistochemistry assays showed KIF2C expression levels in tumors from control or KIF2C-depletion groups. Results are presented as the mean ± standard deviation. Scale bar, 5 mm. ^*P<0.05, ^**P<0.01. KIF2C, kinesin family member 2C; sh, short hairpin; Con, control.