Fig. 1: Pharmacokinetic studies of KVA-D-88 in vivo.
KVA-D-88 was synthesized and administered into mice by either i.v. (1 mg/kg) or oral approach (10 mg/kg). The blood was then collected for determining its pharmacokinetic parameters. (A) Representative molecular structure of KVA-D-88. (B) PK parameters of KVA-D88 in mice with either i.v. injections or oral approach. (C) The concentration-time curve of KVA-D-88 in vivo after either i.v. injections or oral approach.