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. 2021 Aug 10;12:705772. doi: 10.3389/fimmu.2021.705772

Table 5.

The population coverage calculation for peptides with predicted HLA binding.

Peptide HLA allele World population coverage
Selected SARS-CoV-2 peptides against 145 HLAs with known global allele frequency
ESGLKTIL HLA-B*08:01 10.55%
EVLLAPLL HLA-B*51:07 0.12%
NVAITRAK HLA-A*34:02 0.5%
RYPANSIV HLA-A*24:02 21.38%
RYPANSIV HLA-A*24:03 0.49%
RYPANSIV HLA-A*24:07 1.04%
RYPANSIV HLA-C*14:02 3.04%
RYPANSIV HLA-C*14:03 0.87%
RRSFYVYA HLA-B*27:02 1.58%
RRSFYVYA HLA-B*27:03 0.24%
RRSFYVYA HLA-B*27:04 0.79%
RRSFYVYA HLA-B*27:05 4.78%
RFNVAITR HLA-A*33:03 4.78%
RFNVAITR HLA-A*74:01 2.18%
RYPANSIV HLA-A*24:02, HLA-A*24:03, HLA-A*24:07, HLA-C*14:02, and HLA-C*14:03 25.74%
RRSFYVYA HLA-B*27:02, HLA-B*27:03, HLA-B*27:04, and HLA-B*27:05 7.33%
RFNVAITR HLA-A*33:03 and HLA-A*74:01 6.91%
Selected SARS-CoV-2 peptides against the experimentally confirmed HLAs of equivalent IEDB epitopes
RRSFYVYA HLA-B*27:05 5.36%
NVAITRAK HLA-A*11:01 15.53%
RFNVAITR HLA-A*31:01 5.36%
All peptides against all predicted HLAs
All peptides all predicted HLAs 57.41%