Table 2.
Comparison of Various Inflammatory Mediators Expressed in the MDR-PA and S-PA Endophthalmitis Groups by Multiplex ELISA
| Markers | Study Group | Concentration Range (pg/mL) | Detection, n (%) | Group Comparison | Dunn–Bonferroni P |
|---|---|---|---|---|---|
| IL-1α | Controls (A) | 4.33–53.84 | 13 (65) | A vs. B | <0.001 |
| S-PA (B) | 62.1–70219.7 | 12 (100) | A vs. C | <0.001 | |
| MDR-PA (C) | 2420.3–755928.6 | 12 (100) | B vs. C | 0.27 | |
| IL-1β | Controls (A) | — | — | A vs. B | — |
| S-PA (B) | 907.8–9127.3 | 11 (91.6) | A vs. C | — | |
| MDR-PA (C) | 1521–88434 | 12 (100) | B vs. C | 0.02 | |
| IL-10 | Controls (A) | — | — | A vs. B | — |
| S-PA (B) | 56.1–700.6 | 8 (66.6) | A vs. C | — | |
| MDR-PA (C) | 467.4–13034 | 12 (100) | B vs. C | 0.002 | |
| IL-8 | Controls (A) | 0.5–417.6 | 20 (100) | A vs. B | 0.002 |
| S-PA (B) | 18.4–6809.8 | 12 (100) | A vs. C | <0.001 | |
| MDR-PA (C) | 2270.5–32635.2 | 12 (100) | B vs. C | 0.05 | |
| IL-6 | Controls (A) | 1.3–12457.3 | 20 (100) | A vs. B | 0.02 |
| S-PA (B) | 12.6–11877.3 | 12 (100) | A vs. C | <0.001 | |
| MDR-PA (C) | 8319.3–48507.2 | 12 (100) | B vs. C | 0.04 | |
| TNF-α | Controls (A) | 1–16 | 10 (50) | A vs. B | 0.02 |
| S-PA (B) | 6–517 | 12 (100) | A vs. C | <0.001 | |
| MDR-PA (C) | 180–7039 | 12 (100) | B vs. C | 0.01 | |
| IFN-γ | Controls (A) | 1.3–19.4 | 6 (30) | A vs. B | 0.02 |
| S-PA (B) | 4.1–331.6 | 12 (100) | A vs. C | 0.001 | |
| MDR-PA (C) | 12.2–3144.6 | 12 (100) | B vs. C | 0.22 | |
| GM-CSF | Controls (A) | 13.4–157.1 | 10 (50) | A vs. B | 0.08 |
| S-PA (B) | 9.9–1585.7 | 8 (66.6) | A vs. C | 0.08 | |
| MDR-PA (C) | 37.5–1163.4 | 11 (91.6) | B vs. C | 0.75 |
Data represent the average values of duplicate experiments.