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. 2021 Aug 19;62(10):21. doi: 10.1167/iovs.62.10.21

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Copyright 2021 The Authors

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Figure 3. — Longitudinal analysis of DTI parameters in the DBA/2J mouse model of pigmentary glaucoma and the DBA/2J-Gpnmb⁺ control strain. (A, B) FA maps showing the optic nerves (A, closed arrows) and optic tracts (B, open arrows) of the DBA/2J (top) and DBA/2J-Gpnmb⁺ control groups (bottom) at 12 months old. (C, D) Comparisons of FA, axial diffusivity (λ_//), and radial diffusivity (λ_⊥) in the optic nerves (C) and optic tracts (D) between DBA/2J and DBA/2J-Gpnmb⁺ groups at 7, 9, and 12 months old. Post hoc Sidak tests between DBA/2J and DBA/2J-Gpnmb⁺ mice: *P < 0.05, **P < 0.01, ***P < 0.001; between ages within the same strains: ^#P < 0.05, ^##P < 0.01, ^###P < 0.001, ^####P < 0.0001, with orange and blue brackets indicating longitudinal comparisons within DBA/2J and DBA/2J-Gpnmb⁺ groups, respectively. Data are represented as mean ± standard error of the mean.