Table.
Glaucoma | Healthy Control | |||||||
---|---|---|---|---|---|---|---|---|
Model | Species | Strain | Imaging Time Point | IOP (mm Hg) | n | IOP (mm Hg) | n | Sig. |
Microbead | Rat | Sprague-Dawley | 1 month after induction | 27.28 ± 3.01 | 8 | 14.36 ± 0.66 | 8 | ** |
Laser | Mouse | C57BL/6J | 8 months after induction | 28.14 ± 2.49 | 7 | 14.23 ± 2.65 | 6 | ** |
DBA/2J | Mouse | DBA/2J or DBA/2J-Gpnmb+ | 7 months old | 14.73 ± 1.40 | 8 | 11.51 ± 0.31 | 8 | n.s. |
9 months old | 19.66 ± 1.48 | 8 | 9.87 ± 0.41 | 8 | ** | |||
12 months old | 25.19 ± 1.43 | 8 | 10.76 ± 0.40 | 8 | *** | |||
LTBP2 | Cat | Domestic short-hair (F catus) | 4–8 years old | 57.83 ± 8.33 | 3 | 16.56 ± 2.33 | 3 | *** |
TBK1 | Mouse | C57BL/6J | 20 months old | 15.91 ± 1.18 | 4 | 15.72 ± 1.42 | 4 | n.s. |
Data are represented as mean ± standard error of the mean. Sig: Significance; t test between glaucoma and healthy control groups: *P < 0.05; **P < 0.01; ***P < 0.001; n.s. = not significant.