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. 2021 Jul 31;26:44. doi: 10.4103/jrms.JRMS_631_19

Table 2.

Dose adjustment of immunosuppressants following bariatric surgery in transplant patients

Organ transplanted Study (first author, year of publication, reference) Type of bariatric surgery Number of patients Immunosuppressive drug adjustment
Liver Lin 2013[25] Sleeve gastrectomy 9 No change
Lazzati 2015[31] Not mentioned 56 No change
Tsamalaidze 2018[36] LSG 12 No significant change
Kidney Deogracias 2007[45] Biliopancreatic diversion 1 No change
Rogers 2008[46] Gastric bypass surgery 2 Increased dose for sirolimus, tacrolimus, and mycophenolate mofetil
Szomstein 2010[37] Laparoscopic surgery 5 Decreased dose of cyclosporine
Arias 2010[41] Laparoscopic gastric bypass 5 No change
Golomb 2014[18] Sleeve gastrectomy 10 Two increased dose of tacrolimus and one decreased (based on serum level)
Gazzetta 2017[42] Sleeve gastrectomy 6 No change
Heart and kidney Rex 1991[39] Vertical banded gastroplasty 1 Changes based on serum level
Heart Ablassmaier 2002[19] Laparoscopic gastric banding 1 No change
Tsamalaidze 2017[32] Laparoscopic robotic-assisted RYGB, and LSG 2 No change

LSG=Laparoscopic sleeve gastrectomy; RYGB=Roux-en-Y gastric bypass