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. Author manuscript; available in PMC: 2021 Aug 24.
Published in final edited form as: J Pediatr Gastroenterol Nutr. 2019 May;68(5):689–694. doi: 10.1097/MPG.0000000000002227

TABLE 3.

IgG4 staining in eosinophilic esophagitis patients

EoE patients by age group Any positive IgG4 staining, no. (%)* Esophageal level IgG4 staining strong intensity, no. (%) IgG4 staining lamina propria location, no. (%) IgG4 staining epithelium location, no. (%) IgG4 staining focal distribution, no. (%)
Pediatric, n = 16 8/16 (50) Distal 6/7 (86) 7/7 (100) 4/7 (57) 4/7 (57)
Proximal 5/8 (63) 7/8 (88) 4/8 (50) 5/8 (63)
Adult, n = 15 7/15 (47) Distal 3/7 (43) 5/7 (71) 4/7 (57) 5/7 (71)
Proximal 2/5 (40) 3/5 (60) 2/5 (40) 3/5 (60)

EoE = eosinophilic esophagitis

*

Patients with EoE were significantly more likely to stain positively for IgG4 compared to children with reflux esophagitis or healthy controls (15/31 vs 0/8, P = 0.015).