Table 3.
Mean (SEM) axillary temperatures (°C) of male and female preweanling (n = 16 per group) rats on the test day
| Pretreatment: | Saline | RU 24969 (2.5 mg/kg) | ||
|---|---|---|---|---|
| Test Treatment: | Saline | RU 24969 (5 mg/kg) | Saline | RU 24969 (5 mg/kg) |
| 36.34 (0.22) | 31.73 (0.36)a | 36.41 (0.17) | 32.95 (0.27)ab | |
Note: Rats were pretreated with saline or 2.5 mg/kg RU 24969 on PD 17–20, and were then injected with saline or RU 24969 (5 mg/kg) on the test day (PD 22). Data are collapsed over the Home Cage and Activity Chamber conditions.
Significantly different from rats given saline on the test day.
Significantly different from saline-pretreated rats given RU 24969 (5 mg/kg) on the test day.