Fig. 6.
Gastrocnemius RNA-sequencing. (a) Top significantly impacted GSEA hallmark pathways altered by HU in Vehicle compared to AMB and rescued by MET+LEU during hindlimb unloading and reloading, MET and LEU individual effects presented. (b) Top individual genes altered by HU in Vehicle compared to AMB and rescued by MET+LEU during hindlimb unloading and reloading with MET and LEU individual effects presented. Significant pathways were determined by adjusted p<0.05. NES = Normalized enrichment scores. N=4/group.