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. 2021 Aug 24;10(8):e1324. doi: 10.1002/cti2.1324

Figure 1.

Figure 1

(a) Samples and groups [non‐allergic (NA), n = 9; single‐food allergic (SA), n = 10; and multi‐food allergic (MA), n = 7] used in this study. Red lines indicate individual group comparisons carried out, while green lines represent the comparison of NA (n = 9) and combined FA groups (SA and MA, n = 17). 20 025 genes and 770 475 probes are used in transcriptomic and epigenomic analyses, respectively. (b) Heatmap of the 144 differentially methylated probes (DMPs) in the NA/FA comparison. (c) Boxplots of the (i) 77 probes showing higher methylation in FA individuals and (ii) 67 probes showing lower methylation in FA individuals compared with the NA group. Values displayed above boxplots represent P‐values determined by the Mann–Whitney U‐test between groups. (d) PCA plot of 144 DMPs separating the NA and FA groups. (e) PCA plot of 116 differentially expressed genes separating the NA and FA groups.