Table 4. Diagnostic performance of the STANDARD G6PD Test using the manufacturer’s thresholds compared with normalized spectrophotometric reference values, by specimen type.
| Venous | Capillary | P value* | |
|---|---|---|---|
| 30% G6PD-deficient males and females, total study number ND | 1,662 | 1,693 | |
| Sensitivity (95% CI) | 100.0 (93.6–100.0) | 100.0 (93.8–100.0) | 1.00 |
| Specificity (95% CI) | 98.6 (97.9–99.1) | 97.8 (97.0–98.5) | 0.05 |
| 70% G6PD-intermediate females, total study number NI | 911 | 918 | |
| Sensitivity (95% CI) | 96.9 (83.8–99.9) | 94.3 (80.8–99.3) | 1.00 |
| Specificity (95% CI) | 96.5 (95.0–97.6) | 92.3 (90.3–94.0) | 0.01 |
G6PD, glucose-6-phosphate dehydrogenase; ND, total sample size for G6PD deficiency (both males and females); CI, confidence interval; NI, total sample size for G6PD-intermediate performance (all females, not including G6PD-deficient females).
*McNemars P value comparing performance between venous and capillary specimens.