Table 2. Odds ratio for decline in EQ-5D-3L utility score after 2 years of follow-up.

	Patients with Decline in QOL n (%)	Odds ratio (95%CI)	P
Univariable analysis
Group 1	86 (44.8%)	1.52 (1.10 to 2.10)	0.012
Group 2	29 (65.9%)	3.62 (1.9 to 6.88)	<0.0001
Group 3	242 (34.8%)	Reference
Multivariable analysis (Model 1)
Group 1	86 (44.8%)	1.46 (0.94 to 2.25)	0.090
Group 2	29 (65.9%)	2.86 (1.36 to 6.00)	0.006
Group 3	242 (34.8%)	Reference
Multivariable analysis (Model 2)
Group 1	86 (44.8%)	1.45 (0.94 to 2.24)	0.095
Group 2	29 (65.9%)	2.75 (1.30 to 5.81)	0.008
Group 3	242 (34.8%)	Reference
Multivariable analysis (Model 3)
Group 1	86 (44.8%)	1.38 (0.93 to 2.05)	0.106
Group 2	29 (65.9%)	3.47 (1.76 to 6.85)	0.0003
Group 3	242 (34.8%)	Reference

Model 1: Adjusted for age, age at hemodialysis onset, sex, diabetic nephropathy, dialysis vintage, history of myocardial infarction, ischemic stroke, intracerebral hemorrhage or amputation, predialysis body mass index, Kt/V, geriatric nutritional risk index, hemoglobin, C-reactive protein, use of benzodiazepine agents.

Model 2: Adjusted for covariates in Model 1 plus new-onset myocardial infarction, ischemic stroke, intracerebral hemorrhage or amputation during follow-up.

Model 3: Adjusted for all factors in Model 2 except for Kt/V and C-reactive protein.

Abbreviations: CI, confidence interval; EQ-5D-3L, EuroQol 5-Dimensions 3-Levels Questionnaire; QOL, quality of life.