Table 5. Positive and negative predictive values for RBT only, cELISA only, series, and parallel diagnostic testing approaches for two subpopulations using cattle, sheep, and goat model estimates.
Diagnostic approach | Subpopulation | Species | |||||
---|---|---|---|---|---|---|---|
Cattle | Sheep | Goat | |||||
PPV | NPV | PPV | NPV | PPV | NPV | ||
RBT | Pastoralist | 0.840 | 0.985 | 0.859 | 0.996 | 0.798 | 0.990 |
Non-pastoralist | 0.414 | 0.998 | 0.473 | 0.999 | 0.307 | 0.999 | |
cELISA | Pastoralist | 0.913 | 0.975 | 0.538 | 0.980 | 0.653 | 0.977 |
Non-pastoralist | 0.586 | 0.997 | 0.146 | 0.997 | 0.175 | 0.997 | |
Series | Pastoralist | 1 | 0.967 | 1 | 0.979 | 1 | 0.971 |
Non-pastoralist | 1 | 0.995 | 1 | 0.997 | 1 | 0.997 | |
Parallel | Pastoralist | 0.816 | 0.995 | 0.654 | 0.998 | 0.647 | 0.996 |
Non-pastoralist | 0.374 | 0.999 | 0.217 | 1 | 0.171 | 1 |
PPV is positive predictive value and NPV is negative predictive value. RBT is the Rose Bengal plate test. For sheep and goat models, RBT refers to the modified RBT 3:1 serum to antigen ratio. cELISA is the Animal and Plant Health Agency, UK, competitive enzyme-linked immunosorbent assay.