Table 2.
Functional magnetic resonance results and derived parameters.
| wo F | with F | wo/with F | ||||
|---|---|---|---|---|---|---|
| Neutral | Flexion | Neutral | Flexion | Neutral | Flexion | |
| R2* [1/s] | ||||||
| Cortex | 17.7 ± 1.8 | 18.5 ± 1.4 | 17.3 ± 2.3 | 17.5 ± 2.2 | 1.03 ± 0.11 | 1.04 ± 0.10 |
| p | 0.14 | 0.77 | 0.53 | |||
| Medulla | 28.3 ± 2.9 | 27.6 ± 3.6 | 24.0 ± 3.3 | 25.1 ± 4.1 | 1.22 ± 0.17 | 1.11 ± 0.22 |
| p | 0.22 | 0.23 | 0.00077 | |||
| MCR R2* | 1.60 ± 0.27 | 1.48 ± 0.15 | 1.40 ± 0.20 | 1.44 ± 0.22 | 1.17 ± 0.16 | 1.03 ± 0.14 |
| p | 0.015 | 0.39 | 0.0036 | |||
| ASL [mL/100g/min] | ||||||
| Cortex | 299.5 ± 60.1 | 332.0 ± 66.4 | 277.6 ± 80.6 | 336.7 ± 69.8 | 1.10 ± 0.22 | 0.98 ± 0.16 |
| p | 0.051 | 0.027 | 0.16 | |||
| Medulla | 99.2 ± 35.5 | 139.9 ± 59.8 | 81.7 ± 22.1 | 147.6 ± 68.5 | 1.23 ± 0.59 | 1.14 ± 0.54 |
| p | 0.011 | 0.0052 | 0.41 | |||
| MCR ASL | 0.34 ± 0.09 | 0.44 ± 0.15 | 0.32 ± 0.11 | 0.48 ± 0.21 | 1.10 ± 0.39 | 1.04 ± 0.42 |
| p | 0.026 | 0.033 | 0.37 | |||
| ADCD [*10−5 mm2/s] | ||||||
| Cortex | 208 ± 13 | 210 ± 13 | 206 ± 12 | 211 ± 14 | 1.01 ± 0.07 | 0.99 ± 0.05 |
| p | 0.5 | 0.163 | 0.42 | |||
| Medulla | 208 ± 15 | 206 ± 15 | 202 ± 13 | 208 ± 15 | 1.03 ± 0.07 | 0.99 ± 0.07 |
| p | 0.95 | 0.022 | 0.39 | |||
| MCR ADC D | 1.01 ± 0.06 | 0.99 ± 0.05 | 0.98 ± 0.05 | 0.99 ± 0.07 | 1.03 ± 0.07 | 1.01 ± 0.09 |
| p | 0.62 | 0.77 | 0.8 | |||
| FP [%] | ||||||
| Cortex | 11.7 ± 3.3 | 12.9 ± 3.6 | 11.3 ± 4.2 | 11.1 ± 4.9 | 1.06 ± 0.42 | 1.34 ± 0.50 |
| p | 0.5 | 0.34 | 0.076 | |||
| Medulla | 5.9 ± 4.6 | 7.4 ± 4.5 | 10.1 ± 3.6 | 10.7 ± 4.0 | 0.64 ± 0.48 | 0.80 ± 0.64 |
| p | 0.51 | 0.78 | 0.66 | |||
| MCR F P | 0.60 ± 0.51 | 0.54 ± 0.27 | 0.93 ± 0.35 | 1.11 ± 0.62 | 0.72 ± 0.52 | 0.67 ± 0.53 |
| p | 0.63 | 0.16 | 0.6 | |||
Values are given as mean ± standard deviation. p-values are calculated according to Student's t-test. Wo, without; F, furosemide; neutral/flexion denotes hip position; R2*, transverse relaxation rate; MCR, medullary to cortical ratio; ASL, arterial spin labeling; ADCD, pure diffusion coefficient; FP, fraction of perfusion.