Table 3.
Hazard Ratios (HRs) and 95% Confidence Intervals (CI) for the Incidence of Cerebral Infarction According to the Quartile Groups of Serum GGT Levels
| Person-Year | Incidence Cases | Incidence Density (per 10,000 Person-Year) | HR (95% CI) | ||
|---|---|---|---|---|---|
| Unadjusted | Multivariate Adjusted Model* | ||||
| γ-glutamyltransferase | |||||
| Quartile 1 | 219,353.7 | 433 | 19.7 | 1.00 (reference) | 1.00 (reference) |
| Quartile 2 | 232,183.8 | 576 | 24.8 | 1.26 (1.10–1.42) | 1.11 (0.98–1.27) |
| Quartile 3 | 239,004.2 | 716 | 29.9 | 1.52 (1.35–1.72) | 1.39 (1.22–1.58) |
| Quartile 4 | 224,845.8 | 678 | 30.1 | 1.54 (1.36–1.73) | 1.49 (1.29–1.71) |
| P for trend | <0.001 | <0.001 | |||
| Age | 1.10 (1.10–1.11) | ||||
| Gender (female Vs male) | 0.78 (0.70–0.86) | ||||
| BMI | 1.003 (0.989–1.018) | ||||
| Systolic BP | 1.012 (1.010–1.015) | ||||
| Fasting blood glucose | 1.006 (1.005–1.007) | ||||
| Total cholesterol | 1.002 (1.001–1.003) | ||||
| eGFR | 0.997 (0.995–0.999) | ||||
| Smoking amount (pack-year) | 1.007 (1.004–1.010) | ||||
| Alcohol intake | 0.934 (0.828–1.053) | ||||
| Physical activity | 0.857 (0.764–0.961) | ||||
Notes: *Multivariate adjusted model was adjusted for age, gender, BMI, systolic BP, fasting blood glucose, total cholesterol, eGFR, smoking amount (pack-year), alcohol intake and physical activity.