Table 3. Summary of findings in dementia with Lewy bodies.
Author | Imaging modality | Subjects | Summary of findings |
Kantarci et al. [22] | 18F-AV-1451, PiB PET | 19 DLB, 19 AD, 95 HC | 18F-AV-1451 retention in DLB is lesser compared to AD, but higher in the posterior temporoparietal and occipital cortex compared to the control group. |
Gomperts et al. [23] | 18F-AV-1451, PiB PET | 7 DLB, 8 PDD, 9 PD without dementia, 29 HC | Markedly raised 18F-AV-1451 retention in both DLB and PDD compared to the healthy controls, increased tau burden correlates well with the clinical severity. |
Smith et al. [25] | 18F-AV-1451 PET, MRI | 6 DLB, 18 PDD, 11 PD without dementia, 44 HC | Raised parietal 18F-AV-1451 binding in DLB patients, which was linked to abnormality in executive functions in patients. |