TABLE 4.
Histopathologic scoring
| Grade | ATI | IFTA | Infiltrate | Glom. sclerosis | Intim. sclerosis | Hyalinosis | |
|---|---|---|---|---|---|---|---|
| LDKT | Mild | 6/10 | 5/10 | 1/10 | 5/10 | 2/10 | 0/10 |
| Moderate | 2/10 | 0/10 | 0/10 | 1/10 | 1/10 | 0/10 | |
| DDKT | Mild | 4/11 | 4/11 | 1/11 | 4/11 | 2/11 | 1/11 |
| Moderate | 7/11 | 1/11 | 0/11 | 0/11 | 1/11 | 1/11 | |
| P Value | 0.08 | 0.56 | 0.94 | 0.39 | 0.99 | 0.37 | |
| IGF | Mild | 1/5 | 2/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| Moderate | 4/5 | 1/5 | 0/5 | 0/5 | 1/5 | 1/5 | |
| DGF | Mild | 3/6 | 2/6 | 0/6 | 1/6 | 1/6 | 0/6 |
| Moderate | 3/6 | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 | |
| P | 0.30 | 0.45 | 0.25 | 0.14 | 0.49 | 0.23 | |
Histopathologic scoring of LDKT vs DDKT biopsies and of IGF vs DGF biopsies by the Banff criteria for preimplantation biopsies.29
The number of biopsies from each group receiving a score of mild or moderate is shown for each category (no biopsy received a grade of severe in any category) with associated P. Note that for tubular injury, the majority of LDKT biopsies had a mild grade while DDKT biopsies predominantly showed moderate injury; however, there was no appreciable difference in tubular injury scoring between IGF and DGF samples.
ATI, acute tubular injury; DDKT, deceased donor kidney transplant; DGF, delayed graft function; Glom, glomerular; IFTA, interstitial fibrosis and tubular atrophy; IGF, immediate graft function; Intim, intimal; LDKT, living donor kidney transplant.