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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Dev Biol. 2021 Jun 21;478:25–40. doi: 10.1016/j.ydbio.2021.06.008

Figure 1: Ezh2 is efficiently deleted in the dermal mesenchyme by PDGFRαCreER:

Figure 1:

Schematic depicting the skin development program (A). Indirect immunofluorescence of H3K27me3 with DAPI counterstain at various stages of dermal development (B). Schematic illustration of tamoxifen gavage regimen (C) utilized in the study. βgalactosidase staining (D, E) depicting the region of Cre-ER recombinase of R26R expression. Indirect immunofluorescence of H3K27me3 with DAPI counterstain at E10.5 (F, G) and its quantification (H). Solid line demarcates the epidermis from dermis and dashed line demarcates the lower limit of the dermis. Scale bar=100 microns in B and 50 microns in D-G.