Immunohistochemistry (A, B, C, D) of a PP marker, TCF1 (A, B), and an RP marker, TCF4 (D, E), with hematoxylin counterstain. Quantification of TCF1+ (C) and TCF4+ (F) cells in the dermis. The relative quantity of papillary (G) and reticular (H) progenitor markers in E16.5 whole skin between controls and E8.5-DermEzh2. Hair follicle density at E16.5 (I) and E17.5 (J). The relative quantity of secondary HF initiation gene, Noggin (K). Solid line demarcates the epidermis from dermis. Scale bar=100 microns in A, B, D and E.