Figure 2.

Products A and B inhibit SARS-CoV-2 infection of primary human airway epithelial cultures (HAECs). A and B: HAECs derived from donor 1 (A) and donor 2 (B) were exposed to PBS or 50% (v/v) of product A or B and then infected with SARS-CoV-2. After 2 h, virus and compound mixture were removed, and cells were washed in PBS to restore the air-liquid interface. After 1, 2, and 3 days, filters were fixed and stained for SARS-CoV-2 spike protein (green) and cell nuclei (blue) and imaged by confocal microscopy (n = 1 per donor). Shown are merged images. Scale bars represent 100 µm. n.a., not available. C and D: number of infected cells per area was obtained by counting SARS-CoV-2-infected cells within microscopic images. Data represent analysis of 3–5 images per timepoint and condition and are means ± SD.