Table 2.
Perioperative thromboelastography findings in patients undergoing total hip arthroplasty
|
TEG parameter
|
Type
|
Baseline
|
Mid-point of surgery
|
End of surgery
|
Post-op day 1
|
Post-op day 2
|
Post-op day 5
|
| Reaction time (R time, min) | GA | 3.0 (2.6-3.6) | 2.4 (1.8-3.1) | 2.2 (1.8-2.4) | 2.9 (2.1-3.8) | 3.1 (2.3-5.0) | 4.0 (2.4-5.2) |
| SA | 3.0 (2.7-3.8) | 2.5 (1.3-3.0)a | 2.2 (1.4-2.4)b | 2.9 (2.3-41) | 2.8 (2.3-3.7) | 3.8 (2.7-5.7) | |
| Clot kinetics time (K time, min) | GA | 4.2 (3.6-5.1) | 3.3 (2.5-4.1) | 3.0 (2.8-3.4) | 3.9 (2.6-5.6) | 3.7 (2.7-6.4) | 5.3 (3.3-7.1) |
| SA | 4.4 (3.8-5.1) | 3.2 (2.0-4.1)a | 2.8 (2.3-3.3)b | 4.2 (3.2-5.8) | 3.7 (2.9-5.0) | 5.4 (3.9-8.0) | |
| Clot formation angle (degrees) | GA | 36 (30-43) | 50 (39-58) | 43 (34-53) | 44 (33-54) | 46 (31-58) | 41 (33-50) |
| SA | 35 (29-40) | 47 (36-57)b | 45 (40-57)b | 43 (28-49) | 49 (37-57)b | 36 (25-47) | |
| Maximum amplitude (mm) | GA | 62 (56-68) | 68 (63-71) | 65 (54-71) | 71 (66-76)a | 77 (70-81)b | 77 (74-81)b |
| SA | 61 (54-65) | 64 (59-69) | 63 (58-68) | 69 (66-75)b | 74 (70-81)b | 78 (72-82)b | |
| Clot lysis (LY60%) | GA | 5 (3-6) | 4 (3-7) | 4 (2-7) | 6 (2-7) | 5 (3-6) | 3 (1-4) |
| SA | 4 (4-6) | 4 (2-5) | 4 (2-4) | 7 (5-10)a | 5 (4-9) | 3 (2-7) |
All results are presented as median with interquartile range.
a
P < 0.05.
b
P < 0.01 compared to baseline in each group. GA: General anesthesia; SA: Spinal anesthesia; TEG: Thromboelastography; LY60%: Fibrinolysis index. (Normal reference ranges: R time: 4-9 min, K time: 1-3 min. Angle: 59-74 degrees, Maximum amplitude: 55-70 millimeters, LY60: 0%-8%)