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. 2021 Feb 18;24(3):647–661. doi: 10.1038/s41391-021-00328-1

Table 2.

Assessment tools.

Name of test Domain(s) assessed Tool structure Other information
Brief Pain Inventory-Short Form [95] Pain 9-item questionnaire. Each item is rated from 0, no pain, to 10, pain as bad as you can imagine, and contributes with the same weight to the final score

Captures other aspects of pain assessment (site of pain and pain treatment or medication

Requires ~5 min to complete

Functional Assessment of Cancer Therapy-Cognitive Function [96, 97] Perceived cognitive function 50-item questionnaire using four scales (perceived cognitive ability, perceived QoL impairment, perceived cognitive dysfunction, and comments from others)

Specific for cancer patients

Current version 3 (at time of writing)

Validated in patients with cancer

Employs both negative and positive wording

FACIT recommendation is to use 33 items and score the four subscales separately

Functional Assessment of Cancer Therapy-Fatigue [98] Fatigue 13-item fatigue-specific test scale as a subscale adjunct to the 28-item FACT-G (fatigue rated over 7 days)

Designed/validated for cancer patients with anemia

Brief (~10 min) and easy to score

No specific cognitive measures

Functional Assessment of Cancer Therapy-Prostate [99] Health-related QoL (prostate-specific) 12-item prostate cancer-specific test scale as a subscale adjunct to the general 27-item FACT-G health-related QoL questionnaire

Self-administered; requires between 10–14 min to complete

Validated for QoL evaluation in men with PC

Cancer Fatigue Scale [100] Fatigue 15-item scale with three subscales (physical, affective, cognitive) Specifically designed to assess fatigue in patients with cancer; validated by correlation with visual analog scale
Patient Health Questionnaire [101] Depression 9-item screening assessment measuring level of loss of interest, feelings of depression, loss of energy, sleep problems, and concentration problems

May also highlight issues with sleep and fatigue as well as aspects of cognitive functioning

Normally used in original 1-dimensional form though a 2-dimensional form has been used in patients with prostate cancer

Functional Activities Questionnaire [102, 103] Daily functioning (i.e., financial, organizational, social) 10 categories assessing activities of daily living (e.g., bill paying, shopping, cooking, traveling, remembering, current events)

Standardized scale

Commonly used; high sensitivity/specificity

Administered by healthcare professional to a patient or surrogate

European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30 [99] General health status and QoL 30-item cancer-specific measure of health status and health-related QoL; five functional domain scales (physical, role, emotional, social, cognitive), three symptom scales (fatigue, pain, emesis), global health status/QoL scale, and six further-symptom items Current version 3 (at time of writing)
Short-form 36 health survey [99] General health 36-item, 8-dimension scale (physical functioning, social functioning, role limitations due to personal problems, mental health, energy/vitality, role limitations due to emotional problems, pain, general health perception)

Self-administered by healthcare professional interview

Generic health test

No cognitive component

EQ-5D [99, 104] General health

5-domain scale (mobility, self-care, usual function status, pain/discomfort, anxiety/depression)

Intended for disease-specific supplementation

Preference-based

Generic health measure

Construct validity demonstrated in the general population

FACT-G Functional Assessment of Cancer Therapy-General, PC prostate cancer, QoL quality of life.