Fig. 2. Isolated PCa plasma-derived STEAP1 EVs can be detected by nanoscale flow cytometry.
A Representative images of STEAP1 populations as detected by nanoscale flow cytometry in EV fractions isolated from PCa plasma by SEC. EVs were either un-treated, or treated with 1% Triton™ X-100 or 0.5% SDS. B The EV fraction 1 and subsequent fraction 2 was analyzed for STEAP1 in the absence and presence of 1% Triton™ X-100 or SDS 0.5%. Healthy: four samples. PCa: 12 samples. Mann–Whitney test and unpaired t-test. ****p < 0.0001.