Table 1.
Patient characteristics, by study, for analysis of change in urine protein at 6 months
| Study | Intervention | N | Age (SD) | Female (%) | eGFR (SD) | UP (IQR) | FU (IQR) |
|---|---|---|---|---|---|---|---|
| Donadio 1999 | Fish oil | 91 | 38.8 (13.4) | 23 (25.3) | 65.8 (21.7) | 1.9 (1.2, 3.4) | 37.1 (26.4, 44.9) |
| Donadio 2001 | Fish oil | 66 | 46.4 (13.4) | 10 (15.2) | 41.8 (14.1) | 1.6 (0.7, 2.6) | 28.2 (25.1, 38.5) |
| Praga 2003 | RASB | 44 | 31.6 (11.5) | 17 (38.6) | 98.1 (26.5) | 1.7 (1.1, 2.4) | 76.0 (61.0, 129.5) |
| HKVIN | RASB | 107 | 40.1 (9.1) | 77 (72.0) | 75.6 (29.1) | 1.6 (1.1, 2.6) | 34.9 (34.8, 35.1) |
| Maes | IS | 34 | 44.8 (11.3) | 10 (29.4) | 62.2 (18.9) | 1.0 (0.6, 2.7) | 45.0 (33.0, 45.0) |
| Appel | IS | 20 | 37.6 (13.3) | 2 (10.0) | 47.4 (29.2) | 2.3 (1.6, 3.0) | 25.8 (15.1, 28.8) |
| Pozzi 2004 | Steroid | 83 | 38.6 (11.7) | 25 (30.1) | 87.2 (21.6) | 1.9 (1.4, 2.4) | 102.0 (66.0, 126.0) |
| Pozzi 2010 | IS | 190 | 39.3 (12.7) | 55 (28.9) | 74.0 (25.0) | 2.0 (1.5, 2.7) | 72.7 (52.6, 90.3) |
| Pozzi 2013 | IS | 44 | 42.1 (11.6) | 8 (18.2) | 27.9 (7.1) | 2.5 (1.5, 3.9) | 50.3 (35.2, 62.9) |
| Katafuchi | Steroid | 74 | 36.2 (11.4) | 44 (59.5) | 98.5 (21.8) | 1.3 (0.9, 2.6) | 78.0 (60.0, 90.0) |
| Schena | Steroid | 95 | 33.7 (11.1) | 29 (30.5) | 91.3 (23.7) | 1.6 (1.3, 2.5) | 66.0 (42.0, 78.0) |
| STOP-IgAN | IS | 142 | 44.5 (12.3) | 32 (22.5) | 59.5 (27.3) | 1.6 (1.1, 2.1) | 37.6 (37.2, 38.0) |
|
| |||||||
| Overall | 990 | 39.7 (12.5) | 332 (33.5) | 71.9 (29.8) | 1.8 (1.2, 2.6) | 42.6 (34.9, 78.0) | |
Values for categorical variables are given as number (percentage); values for continuous variables, as mean (standard deviation) or median (interquartile range represented as difference between 25th and 75th percentile). N, sample size; GFR, glomerular filtration rate; UP, urine protein in g/day; FU, follow-up in months; RASB, renin-angiotensin system blockade; IS, immunosuppression.