Table 3:
Virtual crossmatch for deceased donor kidney transplants among the United Network for Organ Sharing regions and among centers stratified by annual deceased donor transplant volumes before and after the implementation of 2014 kidney allocation system
UNOS Region |
Pre-KAS | Post-KAS | VXM (post-KAS vs pre-KAS) | ||||
---|---|---|---|---|---|---|---|
Total DDKT | VXM, N (%) | Total DDKT | VXM, N (%) | Change in VXM (%p) | OR for VXM | P value | |
1 | 1,161 | 91 (7.8%) | 1,853 | 213 (11.5%) | +3.7% | 1.5 (1.2, 2.0) | 0.001 |
2 | 4,048 | 83 (2.1%) | 6,283 | 331 (5.3%) | +3.2% | 2.7(2.1,3.4) | <.001 |
3 | 4,422 | 401 (9.1%) | 7,189 | 1,030 (14.3%) | +5.3% | 1.7(1.5,1.9) | <.001 |
4 | 2,719 | 112 (4.1%) | 5,027 | 218 (4.3%) | +0.2% | 1.1(0.8,1.3) | 0.6 |
5 | 5,427 | 1,739 (32.0%) | 8,164 | 3,173 (38.9%) | +6.8% | 1.3(1.3,1.4) | <.001 |
6 | 1,285 | 10 (0.8%) | 1,918 | 12 (0.6%) | −0.2% | 0.8 (0.4,1.8) | 0.6 |
7 | 2,166 | 288 (13.3%) | 3,523 | 541 (15.4%) | +2.1% | 1.2 (1.0,1.4) | 0.03 |
8 | 2,285 | 36 (1.6%) | 3,321 | 283 (8.5%) | +6.9% | 5.8 (4.1, 8.3) | <.001 |
9 | 2,061 | 28 (1.4%) | 3,317 | 216 (6.5%) | +5.2% | 5.1 (3.4, 7.5) | <.001 |
10 | 2,611 | 48 (1.8%) | 3,966 | 73 (1.8%) | +0.0% | 1.0 (0.7,1.4) | 0.9 |
11 | 3,465 | 247 (7.1%) | 5,260 | 459 (8.7%) | +1.6% | 1.2(1.1,1.5) | 0.007 |
Transplant center volumes (DDKT/year) | |||||||
Ql (≤22), n = 54 | 1,236 | 87 (7.0%) | 2,081 | 152 (7.3%) | +0.3% | 1.0 (0.8,1.4) | 0.8 |
Q2 (23–46), n =55 | 4,609 | 326(7.1%) | 6,921 | 570 (8.2%) | +1.1% | 1.2 (1.0,1.4) | 0.02 |
Q3 (47–79), n = 55 | 7,505 | 483 (6.4%) | 13,133 | 1,119 (8.5%) | +2.1% | 1.4(1.2,1.5) | <.001 |
Q4 (≥80), n = 55 | 18,300 | 2,187 (12.0%) | 27,686 | 4,708 (17.0%) | +5.0% | 1.5 (1.4,1.6) | <.001 |
Total | 31,650 | 3,083 (9.7%) | 49,821 | 6,549 (13.1%) | +3.4% | 1.35 (1.3,1.41) | <.001 |
DDKT: Deceased donor kidney transplantation; KAS: Kidney allocation system, VXM: Virtual crossmatch.