Table 5:
Risk comparisons for delayed graft function, early rejection, death censored graft loss and mortality in multivariable models
Variables | Unadjusted (model 1) OR/HR (95% Cl) |
P Value | Adjusted (model 2) OR/HR (95% CI) | P Value | Adjusted (model 3) OR/HR (95% CD | P Value |
---|---|---|---|---|---|---|
DGF | 1.63(1.21, 2.21) | 0.002 | 1.75(1.29, 2.36) | <0.001 | -- | |
DCGL | 0.91 (0.82, 1.01) | 0.08 | 0.99 (0.90, 1.09) | 0.8 | 0.93 (0.83, 1.04) | 0.2 |
Mortality | 1.08 (0.98, 1.19) | 0.1 | 0.99 (0.92, 1.09) | 0.9 | 0.95 (0.86, 1.05) | 0.3 |
Rejection (index hospitalization) | 1.54 (0.87, 2.74) | 0.1 | 1.66 (0.99, 2.79) | 0.06 | 1.38 (0.80, 2.37) | 0.2 |
Graft loss (index hospitalization) | 1.26(0.91–1.75) | 0.2 | 1.31 (0.97, 1.76) | 0.08 | 0.98(0.71,1.33) | 0.9 |
Model 1: Unadjusted
Model 2: Adjusted for KDPI, donor gender, transplant year, import vs local kidney, use of machine perfusion, transplant center volume, recipient factors (age, gender, BMI, race, DM, ESRD etiology, pre-transplant dialysis and duration, prior KT, 0 antigen mismatch, CPRA, induction & CIT
Model 3: Adjusted for DGF in addition to covariates in Model 2.
All models were adjusted for clustering at the transplant center level.
DGF: Delayed graft function; DCGL: Death censored graft loss