Table 2.
Genotypic and allelic distributions of the CC chemokine ligand 4 gene polymorphism (rs10491121) in n (%), regarding tumour location and disease stage among patients with colon cancer
|
Variable
|
Cases
|
Genotype
|
|
|
Allele
|
|
| Right colon | G/G | G/A | A/A | G | A | |
| Stages I + II | 116 | 38 (32.8) | 62 (53.4) | 16 (13.8) | 138 (59.5) | 94 (40.5) |
| Stages III + IV | 78 | 44 (56.4)b | 24 (30.8) | 10 (12.8) | 112 (71.8)a | 44 (28.2) |
| Left colon | ||||||
| Stages I + II | 67 | 23 (34.3) | 34 (50.8) | 10 (14.9) | 80 (59.7) | 54 (40.3) |
| Stages III + IV | 75 | 27 (36.0) | 37 (49.3) | 11 (14.7) | 91 (60.7) | 59 (39.3) |
a
P < 0.05.
b
P < 0.01. CCL4: CC chemokine ligand 4.